Smith's research interests include urban poverty, joblessness, race and ethnicity, social networks and social capital, and intra-group processes. In her new book, Lone Pursuit: Distrust and Defensive Individualism among the Black Poor (Russell Sage Foundation), Smith advances current and enduring debates about black joblessness, highlighting the role of interpersonal distrust dynamics between low-income black jobholders and their jobseeking relations that make cooperation during the process of finding work a problematic affair. In her current project, tentatively titled Why Blacks Help Less, Smith further interrogates the process of finding work by examining racial and ethnic differences in trust dynamics and exploring the social psychological, cultural, and structural factors that generate these differences. In addition to Lone Pursuit, Smith has published a number of articles in such journals as the American Journal of Sociology, Racial and Ethnic Studies, Social Science Research, and The Sociological Quarterly.
Smith has served on the editorial board of the American Sociological Review and is currently a consulting editor with the American Journal of Sociology and Context Magazine. She holds memberships with the American Sociological Association, the Association of Black Sociologists, and the International Network for Social Network Analysis.
In 2007, Smith was a recipient of the Hellman Family Faculty Fund, which supports the research of promising assistant professors who show capacity for great distinction in their fields. In 2002-2003, Smith was a Visiting Scholar at the Russell Sage Foundation in New York City, and Smith was selected as a Fellow for the 2008-2009 academic year at the Center for the Advanced Study of Behavioral Sciences (CASBS).